Savannah Guthrie’s sister Annie and brother-in-law keep low profile in first sighting since mom Nancy’s disappearance Savannah Guthrie’s sister and brother-in-law were photographed for the first time since her mom, Nancy Guthrie, disappeared from her home.

Annie Guthrie and Tommaso Cioni kept a low profile during their drive on Tuesday, in pictures obtained by Page Six.

Savannah’s sibling attempted to cover her face with a pink hoodie while leaving the couple’s Tucson, Ariz., residence.

Cioni was the last person to see Nancy — despite previous reports it was Annie — as he was the one to drop his mother-in-law off at her house around 9:30 p.m. Saturday after dinner, according to the New York Times.

While it is not known when Cioni wed into the Guthrie family, Annie referred to him as her husband — and her “greatest teacher” — in a 2013 interview.

“He is a great manifester,” she told “Women’s Quarterly Conversation” at the time of Cioni, who was born in Italy. “He writes poetry.”

Pima County Sheriff Chris Nanos confirmed on Monday that her home was being treated as a crime scene.

The Los Angeles Times reported the following day that blood had been found on the site, as well as signs of a forced entry.

On Tuesday, News Nation shared a video of what appeared to be a blood trail leading from Nancy’s front door.

Savannah, who has been absent from “Today” as the FBI’s desperate search for her mother continues, released a statement Monday hoping for the “safe return” of her “dear” parent.

She has since requested her Instagram followers pray for Nancy — and her husband, Michael Feldman, told Page Six on Tuesday that there is nothing “new to report.”

Savannah, notably, has dropped out of hosting the Winter Olympics, which kick off on Friday in Italy.

While the NBC personality and brother Camron Guthrie have not been seen amid the crisis, Nanos confirmed on Tuesday that Nancy’s loved ones are “leaning on each other.”

He believes Nancy, who is in urgent need of her medication, was abducted or kidnapped as she “has high blood pressure, [a] pacemaker and cardiac issues,” as listed in 911 dispatch audio, and could not “go 50 yards” on her own.